Gut bugs may decide if your new knee lasts
NCT ID NCT06951477
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at whether the bacteria in your gut (the gut microbiome) is different in people whose knee replacements fail versus those whose knees work well. Researchers will compare gut bacteria in 30 patients needing repeat knee surgery to those with successful implants. They hope to understand if gut health plays a role in infection, loosening, or pain after knee replacement.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could point toward ways to predict or prevent knee replacement failure by targeting the gut microbiome.
What could go wrong
This is a small, early observational study with only 30 participants, so results may not apply to everyone. It looks for patterns, not a treatment.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University Hospital
London, Ontario, N6A5A5, Canada
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••