Gut bugs may decide if your new knee lasts
NCT ID NCT06951477
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at whether the bacteria in your gut (the gut microbiome) is different in people whose knee replacements fail versus those whose knees work well. Researchers will compare gut bacteria in 30 patients needing repeat knee surgery to those with successful implants. They hope to understand if gut health plays a role in infection, loosening, or pain after knee replacement.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could point toward ways to predict or prevent knee replacement failure by targeting the gut microbiome.
- What could go wrong
- This is a small, early observational study with only 30 participants, so results may not apply to everyone. It looks for patterns, not a treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for OSTEOARTHRITIS, KNEE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Hospital
London, Ontario, N6A5A5, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a common painkiller sabotage your knee treatment?
- Can a Mind-Body program ease knee pain and lift mood?
- Which knee implant feels more natural? a trial puts two designs to the test
- Could a quick insulin shot stop Steroid-Induced blood sugar spikes?
- Which Nerve-Blocking technique offers better knee pain relief?
- Knee replacement pain: can a simple injection match a nerve block?