Can a phone app plus Weight-Loss drugs help people shed pounds and improve heart health?

NCT ID NCT07588984

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether combining GLP-1 medications (like semaglutide and tirzepatide) with Noom's app-based behavioral program helps people lose weight and improve heart health markers. Over 2,300 adults will be followed for 24 months, tracking weight, blood sugar, cholesterol, and side effects. The goal is to see how well these approaches work in everyday life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Semaglutide and tirzepatide (GLP-1 medications), combined with Noom's app-based behavioral program

What this could lead to

If successful, this could show that combining GLP-1 drugs with a digital behavioral program leads to better weight loss and heart health in real-world settings.

What could go wrong

This is an observational study, not a randomized controlled trial, so results may be less reliable. Side effects from GLP-1 drugs (like nausea) are common, and long-term weight maintenance is uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Body Weight Obesity obesity disorder Overweight Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Noom, Inc.

    Princeton, New Jersey, 08542, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••