Bladder cocktail aims to stop recurrent UTIs in spinal cord injury
NCT ID NCT07643974
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early study tests whether washing the bladder with an antibiotic (gentamicin) followed by a probiotic (Lactobacillus) can help restore healthy bacteria and prevent urinary tract infections in people with neurogenic bladder due to spinal cord injury, multiple sclerosis, or spina bifida. 48 adults will receive six bladder washes over two weeks, with timing varied to see which schedule works best. The goal is to see if the probiotic can re-colonize the bladder and keep infections away for up to 28 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Gentamicin and Lactobacillus rhamnosus GG (LGG) bladder washes
What this could lead to
If successful, this could point toward a way to reduce frequent urinary tract infections in people with neurogenic bladder, potentially lowering antibiotic use.
What could go wrong
This is a very early Phase 1 trial with only 48 participants, so results may not apply broadly. The approach involves bladder washes, which may be uncomfortable or cause irritation.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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MedStar National Rehabilitation Hospital
Washington D.C., District of Columbia, 20010, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15224, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••