Tiny particles in knee arteries could offer new pain relief for arthritis

NCT ID NCT07537153

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests a procedure called Genicular Artery Embolization for people with mild-to-moderate knee osteoarthritis. Doctors inject tiny particles into arteries that supply the knee lining to reduce blood flow and hopefully ease pain. Fifteen participants will be followed for three years to check safety and effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Embosphere Microspheres (tiny particles injected into knee arteries)

What this could lead to

If it works, this could offer a new, minimally invasive option to ease knee pain and improve function for people with mild-to-moderate osteoarthritis.

What could go wrong

This is a very small, early-phase study with only 15 people, so results may not apply widely. Risks include pain, skin changes, or accidental blockage of other blood vessels.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Northwestern University

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••