Tiny particles in knee arteries could offer new pain relief for arthritis

NCT ID NCT07537153

Recruiting now Symptom relief Sponsor: Northwestern University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 15, 2026 · Updated 4 times

Summary

This study tests a procedure called Genicular Artery Embolization for people with mild-to-moderate knee osteoarthritis. Doctors inject tiny particles into arteries that supply the knee lining to reduce blood flow and hopefully ease pain. Fifteen participants will be followed for three years to check safety and effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Embosphere Microspheres (tiny particles injected into knee arteries)
What this could lead to: If it works, this could offer a new, minimally invasive option to ease knee pain and improve function for people with mild-to-moderate osteoarthritis.
What could go wrong: This is a very small, early-phase study with only 15 people, so results may not apply widely. Risks include pain, skin changes, or accidental blockage of other blood vessels.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KNEE OSTEOARTHRITIS OSTEOARTHRITIS

Contacts and locations

Locations

Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States

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