Can knowing your genetic risk for heart disease push you to live healthier?
NCT ID NCT07833384
First seen Sep 22, 2026 · Last updated Sep 22, 2026
Summary
Researchers at Pennington Biomedical Research Center are testing whether giving African American adults their genetic risk results early in a heart-health program helps them stay engaged. Sixty participants from the Baton Rouge area join a 16-week program with nutrition, cooking, physical activity, and group support sessions. Half receive genetic testing results and counseling at the start; the other half receive them after the program ends. The study measures attendance and looks at changes in diet, exercise, weight, and blood pressure.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- genetic risk information from a saliva-based testing panel
- What this could lead to
- If it works, this could show that sharing genetic risk results early helps people stick with heart-healthy lifestyle programs. That could shape how prevention programs are designed for communities facing high rates of heart disease.
- What could go wrong
- This is a small pilot study with 60 people, so it cannot prove that genetic information changes behavior or prevents disease. Genetic results might not motivate everyone, and the findings may not apply to other groups or settings.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Early phase 1
The earliest testing in people: a first look at safety, in a very small group.
- Participants
-
60 people
The number who actually took part.
- Started
-
Sep 2025
- Finished
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Mar 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 years or older. * Self-identification as African American. * Willing to complete genetic testing using a saliva DNA collection kit. * Willing to participate in a CVD risk reduction behavioral intervention lasting approximately 16 weeks. * Able and willing to provide informed consent. Exclusion Criteria: * Cannot safely engage in physical activity. * Has current knowledge of genetic contributions to CVD that would compromise the study comparison. * Pregnant at the time of eligibility assessment, because the study observes body weight and physiologic outcomes without pregnancy as a confounder.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Pennington Biomedical Research Center
Baton Rouge, Louisiana, 70808, United States
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