New blood test could spot colon cancer in young adults before It's too late

NCT ID NCT06342401

Recruiting now Diagnosis Sponsor: City of Hope Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 08, 2026 · Updated 3 times

Summary

This study is developing a blood test that uses tiny particles called exosomes and machine learning to detect colorectal cancer in people under 50. The test looks for specific microRNA patterns in the blood. Researchers will compare results from 400 people—some with cancer and some without—to see how accurate the test is. If it works, it could offer a non-invasive way to catch this cancer early.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: blood test measuring microRNA from exosomes and cell-free particles
What this could lead to: If successful, this could provide a simple, non-invasive blood test to catch early-onset colorectal cancer sooner, potentially saving lives.
What could go wrong: This is still an early-stage study with 400 participants. The test may not be accurate enough for widespread use, and results need validation in larger, more diverse groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colonic neoplasm colorectal adenocarcinoma colorectal cancer colorectal neoplasm rectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL ADENOCARCINOMA COLORECTAL CANCER COLORECTAL CANCER STAGE I COLORECTAL CANCER STAGE II COLORECTAL CANCER STAGE III COLORECTAL CANCER STAGE IV COLORECTAL NEOPLASMS COLORECTAL NEOPLASMS MALIGNANT

Contacts and locations

Locations

Barcelona University
RECRUITING

Barcelona, Spain
City of Hope Medical Center
RECRUITING

Duarte, California, 91010, United States
Colorectal Surgery, Vall d'Hebron University Hospital, Universitat Autonoma de Barcelona UAB
RECRUITING

Barcelona, Spain
IRCCS San Raffaele
RECRUITING

Milan, Italy
Kawasaki University
RECRUITING

Kawasaki, Japan
Mie University
RECRUITING

Mie, Japan
National Cancer Center Hospital
RECRUITING

Tokyo, Japan
Salamanca Biomedical Research Institute
RECRUITING

Madrid, Spain
Surgery Department, Hospital del Mar, Barcelona, Spain
RECRUITING

Barcelona, Spain
Tokyo Medical and Dental University
RECRUITING

Tokyo, Japan
University of La Laguna
RECRUITING

San Cristóbal de La Laguna, Spain
University of Salamanca-SACYL-CSIC, Salamanca, Spain
RECRUITING

Salamanca, Spain
Yamagata University
RECRUITING

Yamagata, Japan

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