Can exercise rewind the clock? study tests Aging's impact on fitness gains

NCT ID NCT06471569

Completed Knowledge-focused Sponsor: Duke University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 14, 2026 · Updated 2 times

Summary

This study looks at how aging changes the way older adults respond to exercise. Researchers will have 26 people who previously completed a structured exercise program do a 6-month aerobic workout. They will measure changes in insulin sensitivity and heart fitness to see if age affects how much people benefit from exercise.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Aerobic exercise
What this could lead to: If successful, this study could help design better exercise programs tailored to older adults with conditions like prediabetes or obesity.
What could go wrong: This is a small pilot study with only 26 participants, so results may not apply to everyone. The trial is currently suspended, which may delay findings.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder Insulin Resistance Motor Activity Obesity obesity disorder prediabetes syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIOVASCULAR DISEASES INSULIN RESISTANCE OBESITY PREDIABETIC STATE

Contacts and locations

Locations

Duke Center for Living

Durham, North Carolina, 27705, United States

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