Stomach sleeve without surgery shows promise for fatty liver

NCT ID NCT04820036

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at whether a non-surgical stomach reduction procedure (endoscopic sleeve gastroplasty) can improve liver health in people with obesity and advanced NASH (a severe form of fatty liver disease). Twenty adults with obesity and biopsy-confirmed NASH with advanced scarring will have the procedure and be followed for 12 months. Researchers will measure changes in liver function, scarring, and fat content using liver biopsies and imaging.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver fibrotic liver disease metabolic dysfunction-associated steatohepatitis metabolic dysfunction-associated steatotic liver disease Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States