Heart-Kidney hope: new drug trial for High-Risk patients
NCT ID NCT07029503
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tests whether the drug eplerenone is safe and feasible for people with both heart failure (reduced pumping ability) and severe chronic kidney disease. Previous studies excluded such patients due to risks like high potassium. The trial will enroll 40 participants and monitor safety closely, with a plan to manage any problems. If successful, it could pave the way for better treatment in this underserved group.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- eplerenone (Inspra), a drug that helps the heart and kidneys by blocking a hormone that can cause fluid buildup and potassium problems
- What this could lead to
- If this trial succeeds, it could show that eplerenone is safe and helpful for heart failure patients with severe kidney disease, leading to better treatment options for this high-risk group.
- What could go wrong
- This is a small, early pilot trial with only 40 participants, so results may not apply to everyone. There are known risks of high potassium levels, worsening kidney function, and low blood pressure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Department of Cardiology, Danderyd Hospital, Karolinska Institutet
RECRUITINGStockholm, Sweden
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Other studies related to the condition(s) this trial covers.
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