New lung imaging could help tiny preemies breathe easier

NCT ID NCT06609135

Completed Knowledge-focused Sponsor: Lawrence Rhein Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a non-invasive imaging method called electrical impedance tomography (EIT) can predict when very preterm infants (born at 25-29 weeks) are ready to stop breathing support. Researchers placed EIT belts on 20 infants in the NICU to measure lung function. The goal was to see if EIT readings at 31 weeks could predict successful weaning from ventilation by 32-33 weeks. If it works, EIT might help create better, more personalized breathing support guidelines for these fragile babies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to better guidelines for when to wean preterm infants off breathing support, potentially reducing lung damage.
What could go wrong: This is a small, completed observational study (20 infants) that only looks for associations. It does not test a treatment, so it may not change practice on its own.

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Conditions

The condition(s) this trial relates to.

bronchopulmonary dysplasia Premature Birth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRONCHOPULMONARY DYSPLASIA CHRONIC LUNG DISEASE OF PREMATURITY PREMATURE LUNGS

Contacts and locations

Locations

UMASS Memorial Medical Center

Worcester, Massachusetts, 01605, United States

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