Can a Heart-Lung machine save kids with septic shock?
NCT ID NCT03948048
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a heart-lung bypass machine (ECMO) can help children with severe septic shock survive. Researchers will enroll 60 children and track how many leave the hospital alive. They also want to find the best time to start ECMO and which factors affect success.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ECMO (a heart-lung bypass machine)
- What this could lead to
- If it works, this could show that ECMO helps more children survive septic shock and clarify when to start it.
- What could go wrong
- This is a small, early-stage study with only 60 children. ECMO has serious risks like bleeding and infection, and it may not improve survival.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Children'S Hosptial of Fuan University
RECRUITINGShanghai, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Blood markers may foretell brain fog after sepsis
- Can tracking immune chaos in sepsis reveal new treatment targets?
- Blood clot score may predict organ damage in septic shock
- Could a key hormone be missing in septic shock?
- Could a simple mineral cut the need for powerful blood-pressure drugs in septic shock?
- Blood test may forecast life-threatening clots or bleeds on ECMO