EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION

This study compares two blood-thinning medications for patients who need heart-lung machine support after cardiac surgery. Researchers want to see if nafamostat mesilate causes fewer bleeding problems and prevents blood clots better than the standard heparin treatment. The trial …

This study is comparing two different blood-thinning medications (bivalirudin and heparin) for patients who need a heart-lung machine (ECMO) to stay alive. The goal is to see which drug works better to prevent dangerous blood clots while also causing fewer bleeding problems. Rese…

This study is testing if a life support machine called VV-ECMO can be used safely without giving patients strong blood-thinning drugs. It will involve 40 adults with severe lung failure who are already on this machine. The goal is to see if skipping these drugs reduces bleeding r…

This study is testing the safety and performance of a small medical device called the MiniLung petite kit. It is designed to temporarily take over the work of the lungs and heart for critically ill infants and young children who are in severe respiratory or heart failure. Researc…

This study is testing if injecting a child's own mitochondria—the energy-producing parts of cells—into their heart muscle can help reduce damage caused by poor blood flow. The goal is to help children who are on a heart-lung bypass machine (ECMO) recover better and come off the m…

This large, ongoing trial is testing many different new treatments for patients with severe, life-threatening lung failure. It aims to find better ways to help patients breathe, improve survival, and reduce long-term harm from breathing machines. The study will test new drugs, di…

This study is testing a new device to help diagnose a dangerous leg condition called compartment syndrome in sedated patients on life support (ECMO). Because these patients cannot report pain, doctors need better tools to detect the problem early. The study will compare the new c…