EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Clinical trials for EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION explained in plain language.
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ECMO blood thinner showdown: which drug wins?
Disease control Recruiting nowThis study tests two blood thinners, bivalirudin and heparin, in 80 adults on ECMO life support. The goal is to see which drug keeps blood thin enough to prevent clots and bleeding, and which is more cost-effective. Participants are randomly assigned to one of the two drugs withi…
Matched conditions: EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Phase: PHASE2 • Sponsor: Sydney Local Health District • Aim: Disease control
Last updated May 17, 2026 02:53 UTC
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Power boost for tiny hearts: own mitochondria injected to repair ECMO damage
Disease control Recruiting nowThis study tests a new approach to help children on ECMO (a heart-lung machine) recover from heart injury. Doctors will inject the child's own mitochondria (the energy parts of cells) directly into the heart muscle. The goal is to see if this is safe and helps the heart pump bett…
Matched conditions: EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Phase: NA • Sponsor: Boston Children's Hospital • Aim: Disease control
Last updated May 17, 2026 02:43 UTC
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Could a new blood thinner make ECMO safer after heart surgery?
Disease control Recruiting nowThis study compares a drug called nafamostat mesilate to the standard blood thinner heparin in 80 adults who need a heart-lung machine (ECMO) after heart surgery. The goal is to see if nafamostat can prevent dangerous blood clots while causing fewer bleeding problems. Participant…
Matched conditions: EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Phase: NA • Sponsor: Xiaotong Hou • Aim: Disease control
Last updated May 17, 2026 02:39 UTC
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Could pausing the ventilator on ECMO save more lungs?
Disease control Recruiting nowThis study tests whether giving severe ARDS patients on ECMO a near-apneic (almost no breathing) ventilation approach can reduce lung damage compared to standard care. About 280 adults will be randomly assigned to either early apneic ventilation or usual ultra-protective ventilat…
Matched conditions: EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New mini lung kit could save tiny lives in respiratory crisis
Disease control Recruiting nowThis study is testing a new device called the MiniLung petite kit in 20 newborns and children weighing 2 to 8 kilograms who have severe breathing or heart failure. The device is used with a machine that takes over the work of the lungs and heart (ECMO). The goal is to see if it s…
Matched conditions: EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Sponsor: Xenios AG • Aim: Disease control
Last updated May 13, 2026 16:01 UTC
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Can a Heart-Lung machine save kids with deadly sepsis?
Disease control Recruiting nowThis study looks at whether a machine called ECMO can help children with severe septic shock who are not getting better with standard treatment. ECMO works as an artificial heart and lung to support the body. The study will include 60 children and aims to see if ECMO improves sur…
Matched conditions: EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Sponsor: Children's Hospital of Fudan University • Aim: Disease control
Last updated Apr 29, 2026 15:01 UTC
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New blood thinner tested for critical Heart-Lung machine patients
Disease control Recruiting nowThis study compares two blood-thinning medications (bivalirudin and heparin) in adults who need a heart-lung bypass machine (ECMO). Researchers want to see which drug works better to prevent dangerous blood clots while causing fewer bleeding problems. The goal is to find the safe…
Matched conditions: EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Phase: NA • Sponsor: Xiaotong Hou • Aim: Disease control
Last updated Apr 16, 2026 13:01 UTC
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Massive trial aims to find better ways to treat severe lung failure
Knowledge-focused Recruiting nowThis large study is testing multiple new treatments for people with severe breathing failure who need oxygen or a ventilator. It will include up to 6,250 participants and use a flexible design to quickly identify which treatments work best. The goal is to improve survival and red…
Matched conditions: EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC
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New device could save limbs of sedated ECMO patients by catching dangerous leg pressure early
Knowledge-focused Recruiting nowThis study tests a new device that continuously measures pressure in the leg to detect a serious condition called compartment syndrome in patients on ECMO life support. Because these patients are sedated and can't report symptoms, the device may help doctors diagnose the problem …
Matched conditions: EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated May 13, 2026 16:00 UTC
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Could ECMO without blood thinners be safe? new trial aims to find out.
Knowledge-focused Recruiting nowThis study is testing whether a heart-lung machine (ECMO) can be used safely without blood thinners in adults with severe lung failure. About 40 participants will be randomly assigned to receive either standard care with blood thinners or no blood thinners. The goal is to see if …
Matched conditions: EXTRACORPOREAL MEMBRANE OXYGENATION COMPLICATION
Phase: PHASE2, PHASE3 • Sponsor: Damian Ratano • Aim: Knowledge-focused
Last updated May 08, 2026 12:02 UTC