Could a sleep apnea machine fix blood pressure swings in nerve disease?

NCT ID NCT05489575

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether using a CPAP machine (a device that gently blows air through a mask) can safely lower high blood pressure when lying down at night and help reduce dizziness upon standing in people with autonomic failure. About 59 adults aged 40-80 with conditions like Parkinson's disease or multiple system atrophy will spend several days in a research center, receiving both real and sham CPAP to compare effects. The goal is to find a non-drug way to manage these blood pressure problems.

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Conditions

The condition(s) this trial relates to.

hypertensive disorder Hypotension, Orthostatic multiple system atrophy Parkinson disease primary orthostatic hypotension pure autonomic failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Autonomic Dysfunction Center/ Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact