Could a common circulation drug stop strokes before they strike again?

NCT ID NCT07174414

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether adding cilostazol, a drug that improves blood flow, to standard aspirin or clopidogrel therapy can prevent another stroke or heart attack in people who have recently had a stroke or mini-stroke. About 2,000 participants will take either cilostazol or a placebo twice daily for several years. The goal is to see if the combination reduces major cardiovascular events like stroke, heart attack, or vascular death.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cilostazol

What this could lead to

If it works, this could provide a new, affordable way to reduce the risk of another stroke or heart attack in people who have already had one.

What could go wrong

This is a large phase 3 trial, but cilostazol may not reduce events more than placebo, and it carries risks like bleeding or heart-related side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ischemic stroke transient ischemic attack myocardial infarction prevention target stroke disorder prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Stanford University

    Stanford, California, 94305, United States