New monthly shot could simplify mental health treatment

NCT ID NCT07185815

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a long-acting injection of cariprazine given once a month, instead of daily pills, for people with schizophrenia, bipolar I disorder, or major depression. The trial involves 24 clinically stable adults and will check safety, side effects, and how well the drug works. It is still in early stages, so results are not yet known.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cariprazine (long-acting injection)

What this could lead to

If successful, this could offer a convenient once-monthly injection for people with schizophrenia, bipolar disorder, or depression, potentially improving treatment adherence.

What could go wrong

This is an early-phase trial with only 24 participants, so safety and effectiveness are not yet proven. The injection may cause side effects or not work as well as daily pills.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bipolar I disorder major depressive disorder schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mapi Pharma Investigational Site IL-001

    RECRUITING

    Tel Aviv, 6423906, Israel

    Contact

  • Mapi Pharma Investigational Site IL-003

    RECRUITING

    Ness Ziona, 741000, Israel

    Contact

  • Mapi Pharma Investigational Site IL-004

    RECRUITING

    Beersheba, 8461144, Israel

    Contact

  • Mapi Pharma Investigational Site IL-005

    RECRUITING

    Ramat Gan, 56621, Israel

    Contact

  • Mapi Pharma Investigational Site IN-101

    RECRUITING

    Ahmedabad, 380008, India

    Contact

  • Mapi Pharma Investigational Site IN-102

    RECRUITING

    Ahmedabad, 380016, India

    Contact