Scientists lock volunteers in rooms to measure how many calories they burn after eating

NCT ID NCT05545306

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how changing the amount and type of food you eat affects the energy your body uses to digest and process that food. Healthy adults aged 18 to 60 will stay in a clinic for about 35 days, eating only provided meals and spending multiple 24-hour periods in a sealed room that measures their energy use. The goal is to better understand diet-induced thermogenesis, or the calories burned during digestion.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

controlled diets (varying calorie levels and macronutrient balance)

What this could lead to

If successful, this could help scientists better understand how the body burns calories after eating, which may inform future weight management strategies.

What could go wrong

This is an early-stage observational study in healthy volunteers, not a treatment trial. Results may not apply to people with obesity or other conditions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Fasting Obesity obesity disorder Weight Gain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • NIDDK, Phoenix

    RECRUITING

    Phoenix, Arizona, 85004, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••