New Weight-Loss drug cagrilintide shows promise in Late-Stage trial
NCT ID NCT07220642
First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 4 times
Summary
This Phase 3 trial tests whether cagrilintide, a new injectable drug, helps people with overweight or obesity lose weight. About 300 adults will receive either cagrilintide or a placebo for up to 18 months, along with lifestyle counseling. The study measures weight change and waist size reduction.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- cagrilintide
- What this could lead to
- If successful, cagrilintide could become a new weight-loss medication for people with overweight or obesity.
- What could go wrong
- This is a Phase 3 trial, but results may not match real-world use. Side effects are possible, and not everyone may lose significant weight.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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A.O.U. Bologna_ Policlinico S.Orsola Malpighi
Bologna, 40138, Italy
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AOUP Giaccone Palermo
Palermo, Sicily, 90127, Italy
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Brunel Medical Practice
Torquay, Devon, TQ1 4QX, United Kingdom
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CEDIC Centro de Investigación Clínica
CABA, C1060ABA, Argentina
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CIPREC Pueyrredon
Buenos Aires, C1119ACN, Argentina
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Care Clinic Sp. z o. o.
Katowice, 40-568, Poland
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Centre Hospitalier Universitaire de Nantes-Hopital Nord Laennec
Saint-Herblain, 44800, France
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Centre de Recherche Clinique Portes Du Sud
Vénissieux, 69200, France
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Centricity Research Mirabel
Mirabel, Quebec, J7J 2K8, Canada
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Centricity Research Oshawa
Oshawa, Ontario, L1J 2K9, Canada
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Centricity Research Toronto
Toronto, Ontario, M4G 3E8, Canada
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Diablo Clinical Research, Inc.
Walnut Creek, California, 94598, United States
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Drammen sykehus - Vestre Viken HF
Drammen, 3004, Norway
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Florida Inst For Clin Res LLC
Orlando, Florida, 32825, United States
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Fondazione Policlinico Universitario Agostino Gemelli IRCS
Rome, RM, 00168, Italy
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G.A. Research Associates Ltd.
Moncton, New Brunswick, E1G 1A7, Canada
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Hamilton Medical Research Group
Hamilton, Ontario, L8L 5G4, Canada
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Haukeland Universitetssykehus
Bergen, 5021, Norway
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Hunter Diabetes Centre
Merewether, New South Wales, 2291, Australia
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IRCCS Ospedale San Raffaele Milano
Milan, 20132, Italy
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InnoDiab Forschung GmbH
Essen, 45136, Germany
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Midwest Inst For Clin Res
Indianapolis, Indiana, 46260, United States
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Milestone Research
London, Ontario, N5W 6A2, Canada
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NBR Polska Tomasz Klodawski
Warsaw, 00-710, Poland
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North Coast Medical Ltd
Newquay, Cornwall, TR7 1RU, United Kingdom
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Nova Scotia Hlth Halifax
Halifax, Nova Scotia, B3H 1V7, Canada
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Oak Tree Surgery
Liskeard, Cornwall, PL14 3XA, United Kingdom
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Osteo-Medic s.c. A. Racewicz, J. Supronik
Bialystok, 15-351, Poland
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Oviedo Medical Research, LLC
Oviedo, Florida, 32765, United States
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PharmQuest Life Sciences LLC
Greensboro, North Carolina, 27408, United States
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RED-Institut für medizinische Forschung und Fortbildung GmbH
Oldenburg in Holstein, 23758, Germany
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Selma Medical Associates
Winchester, Virginia, 22601-3834, United States
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St. Olavs Hospital HF_Endokrinologisk avdeling
Trondheim, NO-7030, Norway
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StudyMetrix Research LLC
City of Saint Peters, Missouri, 63303, United States
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Sydney Cardiometabolic Centre
Liverpool, New South Wales, 2170, Australia
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Terpa Sp. z o.o. Sp. k.
Lublin, 20-333, Poland
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Univ of Colorado at Denver
Aurora, Colorado, 80045, United States
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Walgreens - Store 11760
Oak Park, Illinois, 60302, United States
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Wendisch - Dahl Hamburg - DZHW
Hamburg, 22607, Germany
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Wharton Medical Clinic Clinical Trials (Hamilton)
Hamilton, Ontario, L8L 5G8, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can Weight-Loss surgery change how medications work?
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- Can shedding pounds reboot the Heart's exercise engine?
- Can stomach surgery alter how painkillers work?