Chilly vests reveal hidden fat secrets that could fight obesity

NCT ID NCT06424132

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study investigates why brown fat, which burns calories to generate heat, stops working when it's warm. Researchers will use cold vests on 8 healthy and obese adults to see how genes and proteins change. The goal is to find new targets for treating obesity and related metabolic problems.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cold vest exposure

What this could lead to

If successful, this could identify new targets for treating obesity and metabolic disorders by reactivating brown fat.

What could go wrong

This is a very small, early-stage study with only 8 participants, so findings may not apply broadly. It focuses on biomarkers, not a direct treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

metabolic disease Obesity obesity disorder type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Rockefeller University

    New York, New York, 10065, United States