New Weight-Loss drug brenipatide enters early human testing

NCT ID NCT07476118

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This early-stage trial is testing a new drug called brenipatide in 150 healthy people with overweight or obesity. Participants receive different doses of the drug or a placebo as injections under the skin. The study lasts about 42 weeks and aims to see how well the drug works for weight loss and how safe it is.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

brenipatide

What this could lead to

If successful, this could point toward a new weight-loss treatment for people with overweight or obesity.

What could go wrong

This is an early Phase 1 trial with only 150 participants, so results may not apply to everyone. The drug may cause side effects or fail to show meaningful weight loss.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fortrea Clinical Research Unit

    RECRUITING

    Dallas, Texas, 75247, United States

    Contact Phone: •••-•••-••••

    Contact

  • Fortrea Clinical Research Unit - Daytona Beach

    RECRUITING

    Daytona Beach, Florida, 32117-5116, United States

    Contact Phone: •••-•••-••••

    Contact

  • Fortrea Clinical Research Unit Inc. - Madison

    RECRUITING

    Madison, Wisconsin, 53704, United States

    Contact Phone: •••-•••-••••

    Contact