Hidden kidney Super-Speed may undermine brain injury treatment

NCT ID NCT07410624

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at a condition called augmented renal clearance (ARC), where the kidneys work too fast and flush out medications before they can help. It involves 512 adults in intensive care with severe brain injuries, strokes, seizures, or meningitis. Researchers will measure kidney function and drug levels to find out how common ARC is and how to adjust doses for better treatment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Ohio State University Wexner Medical Center

    RECRUITING

    Columbus, Ohio, 43210, United States

  • UK HealthCare

    RECRUITING

    Lexington, Kentucky, 40536, United States

  • University of Alberta Hospital

    RECRUITING

    Edmonton, Alberta, T6G 2X8, Canada

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