STATUS EPILEPTICUS

This phase 3 trial tests whether adding ketamine to the standard drug levetiracetam stops prolonged seizures (status epilepticus) more effectively than levetiracetam alone. About 770 people aged 1 and older who are still seizing after initial treatment will receive either the com…

This study tests whether a live video connection between paramedics and pediatric emergency doctors improves care for critically ill children. Paramedics will treat infant mannequins in simulated ambulance scenarios, with some getting video support and others only audio. The goal…

This study aims to create a large database linking brain wave recordings (EEG) and medical records from up to 20,000 epilepsy patients at the University of New Mexico. By combining these two types of information, researchers hope to find patterns that predict seizures and improve…

This study follows 2000 adults who are in a coma or have disorders of consciousness after serious brain injuries like stroke, cardiac arrest, or trauma. Researchers collect medical records and later interview survivors or their caregivers about physical and emotional recovery. No…

This study collects blood, spinal fluid, and brain tissue from 400 people with severe seizures (status epilepticus) or epilepsy linked to brain inflammation (dysimmune encephalitis), plus control patients. Researchers aim to find antibodies and markers of nerve cell death that co…

This study looks at whether using continuous EEG (a brain wave monitor) in the ICU helps people with a severe, hard-to-stop seizure condition called refractory status epilepticus. Researchers will compare patients who get standard care plus continuous EEG to those who get standar…

This study tests whether a set of hospital improvements can help doctors treat children with prolonged seizures (status epilepticus) faster. About 450 children will take part. The goal is to give seizure-stopping medicine within minutes of diagnosis, which may lower the risk of b…

This study looks at a condition called augmented renal clearance (ARC), where the kidneys work too fast and flush out medications before they can help. It involves 512 adults in intensive care with severe brain injuries, strokes, seizures, or meningitis. Researchers will measure …