Daily aspirin may shield hearts after preeclampsia

NCT ID NCT04479072

First seen Nov 11, 2025 · Last updated Jun 22, 2026 · Updated 31 times

Summary

This study tests whether taking a daily low-dose aspirin for six months after childbirth can improve heart function in women who had preeclampsia. Preeclampsia can raise a protein called Activin A, which may harm the heart. The trial will compare aspirin to a placebo in 180 women, measuring heart function and Activin A levels at six months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Chicago Hospital

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Aspirin 81 mg (acetylsalicylic acid)

What this could lead to

If it works, this could point toward a simple, low-cost way to protect heart health in women who have had preeclampsia.

What could go wrong

This is a small, early-phase trial (180 people) testing a biomarker, not a direct health outcome. Aspirin may not improve heart function, and results may not apply to all women.

Conditions

The condition(s) this trial relates to.

cardiovascular disorder hypertensive disorder preeclampsia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.