Can a drug improve blood vessel health in women after preeclampsia?

NCT ID NCT06749418

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at why women who had preeclampsia during pregnancy have higher heart disease risk later in life. Researchers will test a drug called eplerenone on small skin blood vessels in 40 women (some with prior preeclampsia, some without) to see if it improves vessel function. The goal is to understand the underlying mechanisms, not to treat or cure the condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Eplerenone

What this could lead to

If successful, this study could point toward new ways to reduce cardiovascular disease risk in women who had preeclampsia.

What could go wrong

This is a very early, small study (40 participants) testing a drug locally on skin blood vessels, not a treatment. It may not lead to any clinical changes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

preeclampsia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Iowa

    RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••