Daily pill aims to tackle weight and diabetes together

NCT ID NCT07654374

Recruiting now Disease control Sponsor: Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 11, 2026 · Updated 2 times

Summary

This phase 3 study tests aleniglipron, an oral medication taken once daily, for helping adults with obesity or overweight and type 2 diabetes manage their weight over the long term. Participants receive either aleniglipron or a placebo for 76 weeks. The main goal is to see how much body weight changes from the start of the study.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: aleniglipron
What this could lead to: If successful, aleniglipron could offer a convenient daily pill for significant weight loss and better blood sugar control in people with obesity and type 2 diabetes.
What could go wrong: This is a long-term study, and results may not match earlier phases. Side effects or lack of sustained benefit could limit its use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC WEIGHT MANAGEMENT OBESITY OVERWEIGHT TYPE2 DIABETES MELLITUS

Contacts and locations

Show contact details

Study contacts

Contact

Email: •••••@•••••

Locations

ACCOMPLISH-2 Research Site
RECRUITING

Birmingham, Alabama, 35242, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Chandler, Arizona, 85225, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Phoenix, Arizona, 85028, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Sun City West, Arizona, 85375, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Tucson, Arizona, 85741, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Little Rock, Arkansas, 72211, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Escondido, California, 92025, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Fountain Valley, California, 92708, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Lake Forest, California, 92630, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Rolling Hills Estates, California, 90274, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

San Diego, California, 92108, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

San Diego, California, 92123, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Tustin, California, 92780, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Waterbury, Connecticut, 06708, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

Clearwater, Florida, 33756, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

Fort Myers, Florida, 33912, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Jacksonville, Florida, 32216, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

Leesburg, Florida, 34748, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Miami, Florida, 33136, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Ocala, Florida, 34470, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Ocoee, Florida, 34761, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Pembroke Pines, Florida, 33027, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

Atlanta, Georgia, 30329, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Columbus, Georgia, 31904, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Lawrenceville, Georgia, 30046, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Union City, Georgia, 30291, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Woodstock, Georgia, 30189, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

Meridian, Idaho, 83646, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Des Moines, Iowa, 50314, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Iowa City, Iowa, 52242, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Wichita, Kansas, 67218, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

Silver Spring, Maryland, 20901, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Methuen, Massachusetts, 01844, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

Mankato, Minnesota, 56001, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

Minneapolis, Minnesota, 55423, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

Gulfport, Mississippi, 39503, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Ridgeland, Mississippi, 39157, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Chesterfield, Missouri, 63005, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

City of Saint Peters, Missouri, 63303, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

Hazelwood, Missouri, 63042, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Springfield, Missouri, 65807, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

St Louis, Missouri, 63141, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

Missoula, Montana, 59804, United States
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Omaha, Nebraska, 68105, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Las Vegas, Nevada, 89128, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Albany, New York, 12206, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Albany, New York, 12208, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Brooklyn, New York, 11220, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

The Bronx, New York, 10455, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

Charlotte, North Carolina, 28210, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Durham, North Carolina, 27710, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Fayetteville, North Carolina, 28304, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Morehead City, North Carolina, 23730, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

Winston-Salem, North Carolina, 27104, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Columbus, Ohio, 43213, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Moore, Oklahoma, 73160, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Tulsa, Oklahoma, 74133, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Yukon, Oklahoma, 73099, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

Portland, Oregon, 97202, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

Philadelphia, Pennsylvania, 19152, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

Greer, South Carolina, 29651, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Nashville, Tennessee, 37203, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

Austin, Texas, 78704, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Farmers Branch, Texas, 75234, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

Houston, Texas, 77040, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

Houston, Texas, 77054, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

San Antonio, Texas, 78229, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

San Antonio, Texas, 78230, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Wylie, Texas, 75098, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Salt Lake City, Utah, 84107, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Burke, Virginia, 22015, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

Manassas, Virginia, 20110, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
NOT_YET_RECRUITING

Suffolk, Virginia, 23435, United States

Contact Email: •••••@•••••
ACCOMPLISH-2 Research Site
RECRUITING

Renton, Washington, 98057, United States

Contact Email: •••••@•••••

More trials for these conditions

Other studies related to the condition(s) this trial covers.