Can faster brain zaps beat depression in seniors?

NCT ID NCT06854367

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving multiple sessions of magnetic brain stimulation each day works better than the usual one-session-per-day approach for treating depression in people aged 60 and older. About 280 participants will receive active treatment, with some getting the accelerated schedule and others the standard schedule. The goal is to see which method improves mood more quickly and effectively.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

theta burst stimulation (a type of magnetic brain stimulation)

What this could lead to

If it works, this could point toward a faster, more effective treatment for depression in older adults.

What could go wrong

This is an early-stage comparison study, not a final test. The accelerated schedule may not be more effective, and some people may not respond or may experience discomfort from the stimulation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

depressive disorder Depressive Disorder, Treatment-Resistant major depressive disorder mood disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre for Addiction and Mental Healh

    RECRUITING

    Toronto, Ontario, M6J 1H1, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Sunnybrook Health Sciences Centre

    RECRUITING

    Toronto, Ontario, M4N 3M5, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact