New hope for chemo-resistant breast cancer? trial tests immune-boosting drug

NCT ID NCT03979508

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at whether the drug abemaciclib could help people with triple negative breast cancer that didn't respond to standard chemotherapy. The goal was to see if the drug could change the tumor's immune environment to make it more attackable by the body's defenses. The trial was stopped early, but it aimed to find a new option for this aggressive cancer type.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma in situ breast fibrocystic disease ductal breast carcinoma in situ invasive breast carcinoma lobular breast carcinoma in situ triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic in Arizona

    Scottsdale, Arizona, 85259, United States

  • Mayo Clinic in Florida

    Jacksonville, Florida, 32224-9980, United States

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States