Xuanwu Hospital, Beijing

This phase 3 trial tests whether efavirenz, an HIV medication, can help people with Creutzfeldt-Jakob disease (CJD), a rare and fatal brain disorder. About 246 adults with CJD will receive either efavirenz or a placebo daily. The main goal is to see if the drug extends survival t…

This study tests whether a smartphone app that gives personalized temperature health risk warnings can help people who have had a stroke avoid having another one. Over 10,000 adults aged 40 to 80 who recently had a stroke will use the app to learn their risk level and get advice …

This study looks at two treatments for a severe type of stroke that blocks a major artery at the back of the brain. About 518 adults will be grouped based on whether they received a procedure to remove the clot or standard medical care. The goal is to see which approach leads to …

This study tests a smartphone app that gives personalized tips to stroke survivors to help them manage health risks like blood pressure and diet. About 5,000 people who recently had a stroke will use the app or receive standard care. The goal is to see if the app lowers the chanc…

This study tests whether a specific 24-week dietary program can help overweight or obese women with polycystic ovary syndrome (PCOS) achieve regular menstrual cycles and improve overall health. Researchers will compare the special diet to standard care in 160 women aged 18-49. Th…

This early study will test if a gentle, non-invasive brain stimulation technique called temporal interference stimulation can safely help regulate blood pressure. Researchers will enroll 25 adults with either mild untreated hypertension or hard-to-control high blood pressure. Par…

This study tests whether adding the drug sivelestat sodium to standard clot-removal treatment helps people recover better after a stroke caused by a large blood vessel blockage. The drug aims to reduce brain inflammation that can limit recovery even after the clot is removed. Abo…

This early-stage trial tests whether exosomes from umbilical cord stem cells are safe and can help people with mild to moderate Alzheimer's. About 33 participants will receive the treatment or a placebo. The study first checks safety, then looks for signs of cognitive improvement…

This study tests whether adding a drug called GM1 to the standard clot-removal procedure (thrombectomy) helps people recover better after a severe stroke. About 868 adults with a blocked artery in the front part of the brain will receive either GM1 or a placebo, and their recover…

This study will test a new radioactive imaging agent called FBFP to see if it can help doctors better see and understand stroke-related brain changes. Researchers will compare PET/MR scans from 30 stroke patients and 20 healthy volunteers. The goal is to improve diagnosis and mon…

This study will test whether an artificial intelligence (AI) system can accurately assess stroke severity by analyzing video and audio recordings of patients. About 300 adults with a recent stroke will participate, and the AI's scores will be compared to those from trained doctor…

This early-stage study explores whether shining near-infrared light on the brain can help people with mild to moderate Alzheimer's disease. Researchers will measure changes in memory and thinking skills, as well as safety, in 40 adults aged 50-90. The goal is to see if this non-i…

This study tests a gentle, non-invasive brain stimulation technique called tACS in 160 people with mild Alzheimer's or early memory problems. Participants will receive either real or fake (sham) stimulation over several sessions. Researchers will measure changes in memory, thinki…

This study compares two pain medicines given through a pump after brain surgery. The goal is to see if oliceridine causes less nausea than the standard drug sufentanil. About 174 adults having surgery in the back of the head will take part. Researchers will track nausea, pain lev…

This study tests a device worn in the nose during sleep (iNAP) to see if it can improve thinking and memory in people with mild cognitive impairment and moderate-to-severe sleep apnea. About 65 adults aged 50-75 will either use the device nightly for 24 weeks or receive only slee…

This study tests a 6-week prehabilitation program for adults aged 75 and older who need spine surgery. The program includes exercise, nutrition advice, and brain exercises. The goal is to see if it helps them stay independent in daily activities and have fewer complications after…

This study tests whether an artificial intelligence (AI) system can accurately score how well stroke patients recover, compared to the standard method done by trained professionals. About 490 stroke patients will have their recovery scored by both the AI and human experts to see …

This study aims to see if the DiaMem memory test gives consistent results when people take it more than once. Researchers will have 30 adults aged 60 or older take memory tests daily for 6 days. The goal is to understand how reliable the tool is for measuring memory function.

This study observes 120 older adults (age 60+) with various spinal conditions—like scoliosis, stenosis, or herniated discs—and compares their walking patterns and back muscle activity to healthy individuals. Using motion cameras and muscle sensors, researchers aim to identify uni…