Xuanwu Hospital, Beijing

This study tests whether a small surgery done soon after a bleeding stroke can improve recovery. Doctors will use a thin tube to drain the blood clot and give medicine to break it up. The trial will include 750 adults with moderate to large bleeds, comparing this approach to stan…

This study tests whether adding near-infrared light therapy to the drug lecanemab can safely improve thinking and memory in people with mild Alzheimer's disease. About 20 participants will receive either real light therapy or a sham device along with lecanemab for 16 weeks, then …

This study tests whether giving the clot-busting drug Tenecteplase before transferring stroke patients to a specialized hospital can improve their recovery. It involves 572 adults with a major blockage in the brain's front circulation, treated within 4.5 to 24 hours of symptoms. …

This study tests whether a newer clot-dissolving drug (tenecteplase) works better than the current standard (alteplase) when given before a mechanical procedure to remove a large blood clot from the brain. About 850 adults with acute ischemic stroke will be enrolled within 4.5 ho…

This study tests whether a ketogenic diet, a high-fat, low-carb eating plan, can help stop seizures in people with super-refractory status epilepticus—a life-threatening condition where seizures continue despite strong medications. About 84 adults in intensive care will be random…

This study tests whether giving a clot-busting drug (tenecteplase) before transferring patients with a severe type of stroke (basilar artery occlusion) to a specialized hospital can improve recovery. About 316 adults who had a stroke 4.5 to 24 hours earlier will receive the drug …

This study tests whether performing skull surgery early—before dangerous brain swelling occurs—can improve outcomes for people who have had a severe stroke. About 380 adults aged 18 to 75 with large strokes and high risk of swelling will be randomly assigned to receive either ear…

This study tests whether adding a drug called batroxobin to standard blood thinners helps clear blood clots in the brain faster in people with acute cerebral venous thrombosis. About 72 adults will be randomly assigned to receive either the combination or blood thinners alone. Th…

This study tests a two-step approach to find early signs of Alzheimer's in 6,000 adults aged 50 and older who live in the community and have no memory problems. First, participants complete quick digital tests on a phone or computer to check thinking skills and risk. Then, those …

This study aims to develop a blood test to diagnose Parkinson's disease and related disorders more accurately and earlier. Researchers will use a technique called RT-QuIC to detect misfolded proteins in blood samples from about 458 participants, including healthy controls and pat…

This early-stage study tests whether galcanezumab, a drug used for migraines, can help people with mild-to-moderate Alzheimer's disease. Ten participants will receive injections over 24 weeks, and researchers will measure changes in brain proteins and thinking skills. The goal is…

This study tests whether a gentle ultrasound pulse to a specific brain area can improve thinking problems in people with long COVID brain fog. Researchers will compare active ultrasound to a sham (fake) treatment in 40 adults who have had brain fog for at least 4 weeks after COVI…

This study tests whether a common painkiller (oxycodone with acetaminophen) can safely ease chronic pain in people with Alzheimer's disease. Ten participants will take the medication daily for 12 weeks, and researchers will monitor pain levels, daily function, and side effects. T…

This early-stage study tests whether injecting tiny particles from stem cells into the spinal fluid can safely help people with syringomyelia, a condition where fluid-filled cavities form in the spinal cord. The trial includes 18 adults whose spinal cord symptoms have not improve…

This study looks back at medical records of 2,600 stroke patients to see if giving a clot-busting drug between 4.5 and 24 hours after symptoms start is safe and helpful. Researchers want to know if patients treated later can still recover well. This is an observational study, mea…

This study is testing a new MRI technique to see if it can better predict stroke risk in people with narrowed arteries in the brain (intracranial atherosclerotic stenosis). Researchers will measure blood flow pressure using a special MRI scan and track 400 participants for one ye…