Xiangya Hospital Of Central South University

This study compares two types of mesh used to repair a hidden hernia on the opposite side during surgery for a painful hernia. The goal is to see if a biologic mesh, made from pig tissue, causes less chronic pain at 6 months than a standard synthetic mesh. About 90 adults with on…

This study tests whether combining two drugs—camrelizumab (an immunotherapy) and rivoceranib (a targeted therapy)—with or without local treatments like surgery or radiation can shrink tumors in people with advanced liver cancer that has spread to the lungs. About 32 participants …

This study tests whether adding butylphthalide (a neuroprotective drug) to standard clot-busting tenecteplase helps people with mild but disabling stroke recover better. About 1,062 adults aged 18-80 who can be treated within 4.5 hours of symptoms will receive either the combo or…

This phase 4 trial tests whether adding recaticimab to vunakizumab works better than vunakizumab alone for adults with moderate-to-severe plaque psoriasis and high cholesterol. Forty participants will be randomly assigned to receive either the drug combo or vunakizumab plus a pla…

This study will test the drug ivarmacitinib in 1,000 people aged 12 to 75 with moderate-to-severe atopic dermatitis (eczema). Participants take a daily pill for up to 52 weeks, with the option to adjust the dose. Researchers will measure how well the drug clears skin rashes and r…

This study tests a new infrared fluorescence staining technique that could help doctors diagnose prostate cancer faster during a biopsy. The method is compared to the standard frozen section analysis and the gold-standard paraffin section. If successful, it may offer a quicker, m…

This study tests a new blood test that combines genetic sequencing and immune response analysis to quickly tell if dead pancreatic tissue has become infected. Researchers will enroll 200 patients with severe pancreatitis across four hospitals. If accurate, this test could help do…

This study looks at whether three bedside ultrasound techniques—TCCD, ONSD, and ODH—can accurately detect high pressure inside the skull (intracranial hypertension) in people with traumatic brain injury. Researchers will compare these non-invasive methods to the standard invasive…

This study will test whether raising the head of the bed to 15 degrees reduces the chance of low oxygen levels during painless (sedated) gastroscopy and colonoscopy. About 400 adults will be randomly assigned to either a flat or slightly raised position. The goal is to see if thi…

This study tests a new painkiller called tegileridine in 152 adults having abdominal surgery. The goal is to see if it helps the bowels start working again faster than the standard drug morphine. Participants will use a patient-controlled pain pump for up to 72 hours after surger…

This study will test whether giving paracetamol (a common painkiller) instead of a strong opioid (sufentanil) can reduce confusion and delirium in elderly patients after non-cardiac surgery. About 1,092 patients aged 60 and older will be randomly assigned to receive either parace…

This observational study looks at adults with non-small cell lung cancer that has spread to the brain. Researchers want to see if getting radiation and immunotherapy 30 days apart or closer together changes how long the brain tumors stay stable and how long patients live. Partici…

This study will follow about 3,500 adults in China who have atrial fibrillation (an irregular heartbeat) along with metabolic disorders like obesity, diabetes, or high cholesterol. Researchers want to learn how these combined conditions affect risks for stroke, heart failure, and…