New pain drug aims to get your gut moving again after surgery

NCT ID NCT07412223

Not yet recruiting Symptom relief Sponsor: Xiangya Hospital of Central South University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new painkiller called tegileridine in 152 adults having abdominal surgery. The goal is to see if it helps the bowels start working again faster than the standard drug morphine. Participants will use a patient-controlled pain pump for up to 72 hours after surgery, and researchers will track when they can eat solid food and pass gas or have a bowel movement.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Tegileridine (a painkiller similar to morphine but designed to have fewer gut side effects)
What this could lead to: If it works, this could offer a new pain relief option after abdominal surgery that helps the bowels recover faster, reducing hospital stays.
What could go wrong: This is a relatively small, early-phase trial (152 people) comparing against morphine, so results may not apply to all surgeries or patients. The drug may not prove superior or could have unexpected side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative paralytic ileus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PAIN, POSTOPERATIVE POSTOPERATIVE ILEUS

More trials for these conditions

Other studies related to the condition(s) this trial covers.