New study tests if natural mesh can prevent Long-Term pain after hernia surgery
NCT ID NCT07649434
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two types of mesh used to repair a hidden hernia on the opposite side during surgery for a painful hernia. The goal is to see if a biologic mesh, made from pig tissue, causes less chronic pain at 6 months than a standard synthetic mesh. About 90 adults with one painful hernia and one hidden hernia will take part. The results could help surgeons choose the best material to improve long-term comfort.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Biologic mesh (porcine urinary bladder matrix and small intestinal submucosa) and synthetic mesh (self-gripping polyester)
- What this could lead to
- If successful, this could show that biologic mesh causes less long-term pain and discomfort for people with hidden hernias, improving quality of life.
- What could go wrong
- This is a small, early-stage trial with only 90 participants. Previous studies found biologic mesh may have higher recurrence and complication rates, so results may not favor it.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Xiangya Hospital, Central South University
Changsha, Hunan, 410008, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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