Vanderbilt University
Clinical trials sponsored by Vanderbilt University, explained in plain language.
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Brain training may shield kids from inherited depression risk
Prevention CompletedThis study tested whether a program focused on positive emotions could help prevent anhedonia (loss of interest or pleasure) in children aged 8-12 whose mothers have depression. The 73 participants completed a computerized task while their brain activity was measured. The goal wa…
Phase: NA • Sponsor: Vanderbilt University • Aim: Prevention
Last updated Jun 08, 2026 13:04 UTC
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Robot companions fight apathy in Alzheimer's patients
Symptom relief CompletedThis study tested whether a socially assistive robot could reduce apathy in older adults with mild cognitive impairment or Alzheimer's disease living in long-term care. 142 participants were randomly assigned to either usual activities or usual activities plus robot-led sessions.…
Phase: PHASE1, PHASE2 • Sponsor: Vanderbilt University • Aim: Symptom relief
Last updated Jun 16, 2026 23:07 UTC
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Virtual hugs: AR headsets battle senior loneliness
Symptom relief CompletedThis study tested whether using augmented reality (AR) headsets could help older adults feel less lonely. Sixteen older adults and their family members used AR to do activities together over 4 weeks. Researchers measured how easy and enjoyable the technology was to use, and wheth…
Phase: NA • Sponsor: Vanderbilt University • Aim: Symptom relief
Last updated Jun 16, 2026 12:54 UTC
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New therapy boosts language skills in Spanish-Speaking toddlers
Symptom relief CompletedThis study tested a program called EMT en Español that helps Spanish-speaking toddlers (ages 30-36 months) with language delays. The program involves both therapists and caregivers working together to improve the child's communication and school readiness. 81 families participate…
Phase: NA • Sponsor: Vanderbilt University • Aim: Symptom relief
Last updated Jun 15, 2026 19:08 UTC
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New approach cuts risky pills for dementia patients in assisted living
Symptom relief CompletedThis study tested a program called Shed-MEDS that helps safely reduce or stop unnecessary or harmful medications for people with dementia living in assisted living facilities. 18 residents took part, and the program worked with them and their families to decide which medicines co…
Phase: NA • Sponsor: Vanderbilt University • Aim: Symptom relief
Last updated Jun 15, 2026 19:05 UTC
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8,000 volunteers help uncover colon polyp risks
Knowledge-focused CompletedThis study looked at why some people develop colorectal polyps (growths that can turn into cancer) and others do not. Researchers collected blood, urine, saliva, and tissue samples from over 8,000 adults getting a colonoscopy. They also gathered information about lifestyle and he…
Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated Jun 16, 2026 23:08 UTC
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Tutoring boost for struggling First-Graders: study shows promise
Knowledge-focused CompletedThis study looked at whether extra tutoring in reading and math can help first-graders who are behind. 385 students were split into groups that got reading help, math help, both, or their usual school program. The tutoring lasted 15 weeks, and researchers tested the kids before a…
Phase: NA • Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated Jun 16, 2026 23:07 UTC
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New program helps families of kids with autism get the services they need
Knowledge-focused CompletedThis study tested a family navigator program and a smartphone app to help low-resourced families of young children (ages 3-5) with autism find and access services. 52 families took part. The program aimed to improve parents' knowledge, skills, and confidence in getting support fo…
Phase: NA • Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:07 UTC
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Flu shot mystery: why some seniors keep antibodies longer
Knowledge-focused CompletedThis study looked at why some older adults (age 50 and up) maintain flu-fighting antibodies longer after getting the flu vaccine. Researchers enrolled 510 people and measured their immune response over time. The goal was to understand factors that help maintain protection, not to…
Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:05 UTC
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ACL surgery patients studied for arthritis clues
Knowledge-focused CompletedThis study followed 432 people who had ACL knee surgery to learn why some develop arthritis years later. Researchers checked knee X-rays and function at 2 and 10 years after surgery. The goal is to find which injuries, repairs, or patient traits raise arthritis risk. No new treat…
Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated Jun 11, 2026 12:09 UTC
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New program helps affordable housing residents plan their future medical care
Knowledge-focused CompletedThis study tested a new program that helps people living in affordable housing plan their future medical care in a way that is sensitive to past trauma. Thirty adults who did not have an advance directive took part. The goal was to see if the program helped them understand and pa…
Phase: NA • Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated Jun 02, 2026 11:58 UTC