Vanderbilt University
Clinical trials sponsored by Vanderbilt University, explained in plain language.
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Diabetes drug may boost weight loss by targeting Brain's reward center
Disease control OngoingThis study looks at whether adding a low dose of the diabetes medication insulin detemir to a low-calorie diet helps obese adults with type 2 diabetes lose more weight and improve brain function related to food pleasure. About 240 participants will be split into two groups: one o…
Phase: NA • Sponsor: Vanderbilt University • Aim: Disease control
Last updated May 01, 2026 15:58 UTC
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New fraction program aims to boost math skills in 4th graders
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at how well a fraction teaching program works for 4th-grade students, both those with and without math learning difficulties. About 2,210 students will take part, with some teachers using the program and others teaching normally. The goal is to see if the program…
Phase: NA • Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated May 01, 2026 20:42 UTC
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Hidden danger in the ICU: why half of patients leave with lasting muscle damage
Knowledge-focused OngoingThis study looks at why many ICU patients suffer from severe muscle weakness that can last for months or years. Researchers will use muscle biopsies, ultrasound, and strength tests on 50 critically ill adults to find better ways to diagnose and track this condition. The goal is t…
Phase: NA • Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC
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Massive study aims to unlock secrets of depression and psychosis
Knowledge-focused ENROLLING_BY_INVITATIONThis study is collecting DNA, brain images, and other biological samples from 2,000 people with major depression, bipolar disorder, or psychotic disorders, as well as healthy volunteers. The goal is to understand the physical and genetic factors behind these conditions to help ta…
Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated May 01, 2026 16:00 UTC
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POTS puzzle: could antibodies be the missing link?
Knowledge-focused OngoingThis study looks at whether people with Postural Orthostatic Tachycardia Syndrome (POTS) have higher levels of certain antibodies compared to healthy individuals. Researchers will also check if those who developed POTS after a viral infection are more likely to have these antibod…
Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated May 01, 2026 15:57 UTC
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POTS Patients' kidneys may not hold salt like healthy people
Knowledge-focused OngoingThis study looks at whether people with Postural Orthostatic Tachycardia Syndrome (POTS) have trouble keeping salt in their bodies compared to healthy people. Researchers will measure salt levels in urine and stress hormones. The goal is to better understand the condition, not to…
Phase: NA • Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated May 01, 2026 15:57 UTC
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Lung biomarkers could revolutionize pulmonary hypertension care
Knowledge-focused OngoingThis study looks at whether measuring certain substances in the blood across the lungs can help doctors choose better treatments for people with pulmonary hypertension (high blood pressure in the lungs). About 100 adults undergoing a standard heart-lung test will also have these …
Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:05 UTC
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Fatty liver secrets revealed: scientists hunt for clues in biopsies
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to identify which types of fats and proteins are linked to more severe nonalcoholic fatty liver disease (NAFLD). Researchers will analyze liver tissue samples from 45 adults undergoing abdominal or bariatric surgery. No treatment is given; the goal is simply to le…
Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:02 UTC