Diabetes drug may boost weight loss by targeting Brain's reward center

NCT ID NCT01239550

First seen Jan 24, 2026 · Last updated Jun 12, 2026 · Updated 21 times

Summary

This study looks at whether adding the medication insulin detemir to a low-calorie diet helps people with type 2 diabetes and obesity lose more weight. It also checks how the drug affects brain areas linked to food pleasure and mood. About 240 adults aged 31-60 will be split into two groups: one on diet only, the other on diet plus insulin detemir, and followed for 26 weeks with scans and blood tests.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OBESITY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Vanderbilt University

    Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.