University Of Utah

This early-phase study tested a combination of two drugs—nivolumab (an immunotherapy) and Radium-223 (a radioactive drug)—in 39 men with advanced prostate cancer that no longer responds to hormone therapy and has spread to the bones. The main goals were to check safety and see if…

This study tests whether adding the immunotherapy drug nivolumab after standard chemo-radiation can help prevent bladder cancer from coming back. About 200 adults with localized muscle-invasive bladder cancer who cannot have bladder removal surgery are taking part. The main goal …

This study tests a program called FAMS-T1D for young adults aged 18-24 with type 1 diabetes. The program helps them set goals and get support from a friend or family member. Researchers want to see if it improves blood sugar control, diabetes self-care, and reduces diabetes-relat…

This study tests a drug called enfortumab vedotin, alone or with other medicines, in men with advanced prostate cancer that no longer responds to hormone therapy. The goal is to see if the drug can shrink tumors or lower cancer markers. The trial involves 34 participants and is c…

This study tests whether giving immunotherapy (durvalumab) and chemotherapy at different times works better than the usual schedule for people with advanced non-squamous lung cancer. About 43 adults who have not had these treatments before will be randomly assigned to one of two …

This study reviews 100 patients with open-angle glaucoma who had two minimally invasive surgeries (Hydrus microstent and iTrack canaloplasty) along with cataract surgery. Researchers want to see if this combination lowers eye pressure and reduces the need for glaucoma drops more …

This early-phase study looks at whether the diabetes drug metformin can help older adults regain thigh muscle and function after a hip fracture. Sixty people aged 60 and older who had surgery for a hip fracture will take either metformin or a placebo daily for 4 months. The main …

This study looks at whether watching short videos with coping strategies can help people feel less pain and distress after surgery for abdominal cancer. About 95 adults will be assigned to one of three video-based approaches, including mindfulness or other support methods. Partic…

This study aimed to see if a special video game, controlled by breathing in and out, could help children aged 4-11 feel less anxious when getting anesthesia through a mask. The game was designed to encourage steady breathing and distract kids from fear. However, the study was wit…

This study looks at whether special stretching exercises for the vocal folds can help people reach higher and lower pitches and keep their voice steady. Researchers will test 120 adults who do not have voice problems or professional singing training. The goal is to understand how…

This study looks at whether a web-based decision aid helps parents of unborn or newborn babies with life-threatening congenital heart disease make informed medical choices. About 135 parents will be randomly assigned to use the decision aid alone or with an extra values-clarifica…

This study looks at whether special MRI scans can be used safely during surgery to remove brain tumors called gliomas. About 53 adults with suspected gliomas will take part. Some will get the advanced scans before and during surgery, while others will have standard care. The goal…

This study looks at whether using two metal implants (plates or rods) to fix a broken thigh bone near the knee works better than using just one in people aged 60 and older. The goal is to see if a larger study is possible by checking how many people join, follow the plan, and com…

This study tracks the physical stress that orthopedic surgeons experience while performing surgery. Researchers will measure the surgeons' heart rates before and during operations to see how their bodies respond. The goal is to better understand the demands of surgery on the medi…

This study looks at how sleep and daily body rhythms impact memory and thinking in couples over age 50, where one partner has mild memory problems. Researchers will track sleep patterns and test memory using smartphone tasks. The goal is to understand how sleep habits shared by p…

This study looks at whether parts of walking boots can be safely reused for people healing from foot or ankle injuries. About 60 patients will be followed to check for skin problems like blisters or rashes. The goal is to see if reusing these boots is safe and to help reduce medi…

This study was designed to test whether giving methadone during breast reconstruction surgery could lower the need for other opioids and improve pain control afterward. It was planned for women who had mastectomies for breast cancer or prevention. However, the study was withdrawn…

This study looks at how femoroacetabular impingement (FAI) changes the way the hip joint moves. Researchers will compare movement patterns between people with FAI and those without. The goal is to better understand the condition, not to test a treatment. About 36 participants wil…