New drug combo aims to shrink tough prostate tumors

NCT ID NCT04109729

First seen Nov 21, 2025 · Last updated Apr 28, 2026 · Updated 11 times

Summary

This early-phase study tested a combination of two drugs—nivolumab (an immunotherapy) and Radium-223 (a radioactive drug)—in 39 men with advanced prostate cancer that no longer responds to hormone therapy and has spread to the bones. The main goals were to check safety and see if the treatment could reduce tumor DNA in the blood. The study is now complete, and results will help guide future research.

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Contacts and locations

Locations

  • Huntsman Cancer Institute at University of Utah

    Salt Lake City, Utah, 84112, United States

Conditions

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