University Of Manchester

This study aims to learn how tumors and healthy tissues change during radiotherapy by taking detailed MRI scans at each treatment session. About 250 cancer patients and 10 healthy volunteers will participate. Researchers will also collect blood and urine samples to find biologica…

This study aims to prove that a gene test can identify oxygen-starved (hypoxic) tumours in real time for bladder and prostate cancer patients. About 30 participants will provide tumour samples and blood, plus undergo MRI scans. If successful, doctors could tailor stronger treatme…

This study will follow 600 people with immune-mediated inflammatory diseases (like arthritis or lupus) to see how heart disease develops. Researchers will check blood markers and health records to find early warning signs. The goal is to better predict and prevent heart problems …

This study looks at how well the knee works 6 months after a type of cartilage repair surgery called autologous chondrocyte implantation (ACI). Researchers will measure knee movement, balance, and walking in 47 adults before and after surgery. The goal is to help doctors and pati…

This study is creating a secure database of health information from 2,500 people with hypertrophic cardiomyopathy (HCM), a common inherited heart condition. Researchers will collect data from medical records, including heart scans, blood tests, and genetics, to better understand …

This study aims to improve an AI system called Patchs that helps GP practices decide how urgently patients need care. Researchers will analyze data from over 226,000 patients to make the AI more accurate and check if it treats everyone fairly. The goal is to help patients get the…

This study aims to find factors that may cause pregnancy loss between 20 and 28 weeks, such as sleep position, smoking, or caffeine. Researchers will compare 316 women who experienced an early stillbirth with 632 women who had a healthy pregnancy. The goal is to identify changes …

This early study tests a new graphene-based electrode for brain mapping during surgery to remove brain tumors. Ten adults with glioma will have the device used alongside standard monitoring to check its safety and how well it records brain signals. Some participants who are awake…