University Medical Centre Ljubljana

This study looks at whether the drug vericiguat can improve heart function in adults with stable heart failure with reduced ejection fraction (HFrEF). About 60 participants will either take vericiguat plus their usual medications or just their usual medications. Researchers will …

This study tests whether starting two diabetes drugs early (metformin plus either semaglutide or empagliflozin) works better than metformin alone for people recently diagnosed with type 2 diabetes. About 90 adults will take the pills daily for 26 weeks and wear a continuous gluco…

This study tests whether a 7-day course of doxycycline works as well as the standard 14-day course for people with multiple Lyme disease rashes (erythema migrans). About 200 participants will be randomly assigned to one of the two treatment lengths. Researchers will track symptom…

This study compares different doses and lengths of amoxicillin treatment for people with erythema migrans, the classic Lyme disease rash. About 200 participants will be randomly assigned to different treatment schedules. The goal is to see which regimen best prevents later Lyme s…

This study tests a personalized stem cell therapy for 10 people with advanced heart failure who already have a mechanical heart pump (LVAD). Two months after LVAD surgery, patients receive their own stem cells injected into the heart. Researchers will check if this improves heart…

This study looks at whether adding resistance training (like squats and pulling exercises with weights) to usual cycling workouts helps women with coronary artery disease improve their fitness and muscle mass more than cycling alone. About 50 women will take part in a 12-week car…

This study tests whether the steroid dexamethasone can reduce brain damage and long-term disability in adults hospitalized with tick-borne encephalitis. About 200 participants with confirmed infection and signs of brain or spinal cord inflammation will receive either dexamethason…

This study tests whether dapagliflozin, a drug used for diabetes, can prevent heart damage caused by anthracycline chemotherapy in breast cancer patients. About 100 women will receive either dapagliflozin or a placebo daily during their chemo. Researchers will monitor heart funct…

This study compares three sedatives (ketamine, nalbuphine, and dexmedetomidine) in 60 children aged 6 months to 3 years who need stitches removed after cleft lip or palate surgery. The goal is to see which drug works fastest and safest, and which makes the procedure easiest for t…

This study follows 250 children and adults with CTNNB1 neurodevelopmental syndrome to track their mental, physical, and social development over time. By collecting data through assessments and questionnaires, researchers hope to better understand the condition and improve care. T…

This study looks at whether placing a newborn directly on the mother's chest right after a planned C-section helps the baby adapt to life outside the womb. Researchers will measure heart rate patterns in 80 full-term babies and their mothers to see if skin-to-skin contact reduces…

This study looks at how the body controls blood pressure and heart rate in healthy adults and older adults with high blood pressure. Researchers will measure heart activity and artery stiffness during standing and exercise. The goal is to better understand these processes and hel…

This study is observing how patients with sinonasal and skull-base tumours are treated at a specialist ear, nose, and throat centre. Researchers will track 120 participants to understand the number of cases, treatment results, and patients' quality of life. The goal is to gather …

This study looks at whether what patients expect before treatment for early Lyme disease (a red rash called erythema migrans) influences how well they recover. Researchers will follow 200 patients for up to a year, checking for lingering symptoms and comparing them with healthy p…

This study looks at how tirzepatide, a weight-loss drug, affects the muscles of women with obesity. Thirty premenopausal women will receive either the drug or a placebo for 24 weeks. Researchers will measure muscle strength, size, and quality using scans and small tissue samples.…

This study looks at how doctors manage serious infections of the ears, nose, throat, and neck in children and adults. Researchers will collect information from 2550 patients treated at a hospital in Ljubljana, Slovenia, to understand current treatment practices. Participants rece…