Can your own stem cells help a failing heart heal?

NCT ID NCT06154044

Recruiting now Disease control Sponsor: University Medical Centre Ljubljana Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot trial tests whether a patient's own stem cells can help the heart muscle recover in people with advanced chronic heart failure who already have a mechanical heart pump (LVAD). Ten patients will receive their own CD34+ stem cells injected into a heart artery. Researchers will measure changes in heart function, walking ability, and quality of life over six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: CD34+ stem cells (the patient's own blood stem cells)
What this could lead to: If it works, this could point toward a way to help heart muscle recover in people with advanced heart failure who need a mechanical heart pump.
What could go wrong: This is a very small early-phase trial with only 10 people, so results may not apply to everyone. Stem cell injections carry risks like infection or heart damage, and the therapy may not improve heart function.

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Conditions

The condition(s) this trial relates to.

dilated cardiomyopathy heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE MECHANICAL CIRCULATORY SUPPORT

Contacts and locations

Locations

University Medical Center Ljubljana
RECRUITING

Ljubljana, 1000, Slovenia

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