Universitätsklinikum Hamburg-eppendorf

This early-stage trial tested a new two-part vaccine designed to treat chronic hepatitis B. It involved 26 healthy adults to check safety and immune response. The vaccine uses a protein first shot followed by a booster to teach the immune system to attack the virus.

This study tested whether giving each patient a personalized blood flow target during major abdominal surgery could lower the risk of serious complications like kidney injury, heart attack, severe infections, or death within a week after surgery. Over 1,100 high-risk adults (aged…

This study tested if inflatable leg sleeves (pneumatic leg compression) can reduce the amount of blood pressure medication needed during non-cardiac surgery. 238 adults aged 45 and older took part. The goal was to see if this simple device helps maintain stable blood pressure wit…

This study tested a short-term talking therapy (psychodynamic psychotherapy) for 24 adults with advanced solid tumors and high psychological distress. The goal was to see if the therapy is safe, acceptable, and feasible, not to cure the cancer. Results will help design larger stu…

This study tested whether a nerve block (serratus anterior plane block) can reduce pain and the need for strong painkillers after minimally invasive mitral valve repair. 78 adults having this heart surgery were randomly assigned to receive either the nerve block or a placebo. The…

This study tested a non-invasive brain stimulation technique called tACS in 20 stroke survivors who had hand and arm weakness. The goal was to see if it could improve communication between brain areas involved in movement. Participants received real or fake stimulation while thei…

This study looked at why some people have trouble stopping antidepressants. Researchers wanted to see if a person's expectations about stopping the drug play a role, separate from the drug's physical effects. 56 adults who were already doing well on antidepressants were randomly …

This study tested whether a gentle, non-invasive brain stimulation technique called tDCS could change brain activity and reduce symptoms in 15 people with cervical dystonia (neck muscle spasms). Participants received real or fake stimulation, and researchers measured brain signal…

This study tested a German version of a questionnaire that measures how well parents and their children (ages 10-18) communicate. Over 2,300 families participated, and researchers checked if communication quality was linked to teens' physical symptoms and mental health. Two years…

This study looked at how rising temperatures affect people with chronic conditions like heart disease, diabetes, and depression. Researchers from Germany and Italy surveyed 176 adults to see what health problems they had during heat and how well they protected themselves. The goa…

This registry collected information and biological samples from 354 children and young adults (ages 0-21) diagnosed with medulloblastoma, CNS-PNET, or ependymoma. The goal was to improve diagnostic quality through expert review and to gather data for future research. No new treat…

This study looked at two non-invasive methods (NIRS and TCD) to monitor how well the brain controls its own blood flow during major non-cardiac surgery. The goal was to see which method works better and whether keeping blood pressure in a certain range can reduce the risk of conf…

This study tested whether a continuous finger-cuff blood pressure monitor could reduce episodes of dangerously low blood pressure during non-cardiac surgery better than the standard arm cuff that measures pressure every few minutes. Researchers enrolled 930 low-to-moderate risk a…