Universitätsklinikum Hamburg-eppendorf

This study aimed to check how long the Ebola vaccine (VSV-EBOV) protects people at risk of exposure, like lab workers or healthcare staff. It also planned to test if a booster shot strengthens immunity. The trial was withdrawn before enrolling any participants, so no results are …

This study tests a combination of four drugs (isatuximab, carfilzomib, lenalidomide, and dexamethasone) in 246 people newly diagnosed with high-risk multiple myeloma. The goal is to see if this treatment can make cancer undetectable at a deep level. Participants receive the drugs…

This study compares two ways to replace a narrowed heart valve in people with severe aortic stenosis who are at intermediate risk for surgery. About 1,400 participants will be randomly assigned to get either a less invasive TAVI procedure or open-heart surgery (SAVR). The main go…

This study is for children aged 3 to 22 with medulloblastoma, a type of brain tumor. It aims to find the best treatment based on the tumor's genetic profile, with the goal of improving survival and reducing long-term side effects. Participants receive different treatments dependi…

This study looks at information from 1,785 adults who had a breathing tube placed during anesthesia. The goal is to create a standard set of key details that doctors can use to alert future teams if a patient had a difficult airway. By making these alerts more consistent and digi…

This study tests a web-based tool called gp-multitool.de that helps family doctors follow national guidelines for older patients with multiple chronic conditions like diabetes, heart disease, and depression. About 659 patients from various doctor practices in Germany are taking p…

This study looks at data from 423 adults having surgery to create a new, more accurate way to predict when facemask ventilation (helping a patient breathe) might be difficult. The goal is to replace current guesswork with a simple, objective score that doctors can use to prepare …

This study looks at whether brain scans can help predict which people with migraine will respond to a class of drugs called CGRP antibodies. Researchers used MRI to measure brain structure, activity, and blood flow in 219 adults with frequent migraine before and after 12 weeks of…

This study uses brain scans to see how the brainstem and other brain areas respond to mild electrical pulses on the face and arm in 40 healthy volunteers. The goal is to map pain and touch pathways to better understand migraine disorders. No treatment or medication is involved.