Brain scans may unlock migraine treatment success

NCT ID NCT06633484

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether brain scans can help predict which people with migraine will respond to a class of drugs called CGRP antibodies. Researchers used MRI to measure brain structure, activity, and blood flow in 219 adults with frequent migraine before and after 12 weeks of treatment. The goal is to find brain-based markers that separate responders from non-responders, which could lead to more personalized migraine care.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • IRCCS Mondino Foundation

    Pavia, Italy

  • University Medical Center Hamburg-Eppendorf

    Hamburg, 20246, Germany

  • Vall d'Hebron Institute of Research

    Barcelona, Spain

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