New drug cocktail aims to crush High-Risk myeloma

NCT ID NCT03104842

First seen May 19, 2026 · Last updated May 20, 2026 · Updated 1 time

Summary

This study tests a combination of four drugs (isatuximab, carfilzomib, lenalidomide, and dexamethasone) in 246 people newly diagnosed with high-risk multiple myeloma. The goal is to see if this treatment can make cancer undetectable in the bone marrow. Participants receive the drugs in three phases: induction, consolidation, and long-term maintenance.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MULTIPLE MYELOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Asklepios Altona

    Hamburg, Germany

  • Campus Benjamin Franklin Charite Berlin

    Berlin, Germany

  • Johanniter-Krankenhaus Bonn

    Bonn, 53113, Germany

  • Kliniken Maria Hilf GmbH, Klinik für Hämatologie, Onkologie und Gastroenterologie

    Mönchengladbach, 41063, Germany

  • Klinikum Osnabrück

    Osnabrück, Germany

  • Philipps-Universität Marburg

    Marburg, 35032, Germany

  • St. Antonius Hospital

    Eschweiler, Germany

  • Städt. Kliniken Bielefeld Klinikum Mitte

    Bielefeld, Germany

  • Uniklinik Köln

    Cologne, Germany

  • Uniklinikum Chemnitz

    Chemnitz, Germany

  • University Hospital Hamburg Eppendorf

    Hamburg, Germany

  • University Hospital Heidelberg

    Heidelberg, Germany

  • Universitätsklinikum Essen

    Essen, Germany

  • Universitätsklinikum Tuebingen

    Tübingen, Germany

  • Universitätsmedizin der Johannes Gutenberg-Universität Mainz

    Mainz, D-55131, Germany

  • Vivantes Am Urban

    Berlin, 10967, Germany

  • Vivantes Klinikum Neukölln

    Berlin, Germany

Conditions

Explore the condition pages connected to this study.