Thomas Jefferson University

This study is testing a new combination of three drugs—navitoclax, venetoclax, and decitabine—for patients with a high-risk type of blood and bone marrow cancer called myelodysplastic syndrome (MDS) that has come back or hasn't responded to standard treatments. The main goals are…

This study is testing whether a phone-based coaching program can help men on hormone therapy for prostate cancer. Participants work with a coach to gradually extend their overnight fasting period, aiming for 16 hours each night, and report their progress via text messages. The go…

This study is testing whether N-acetyl cysteine (NAC), an antioxidant supplement, can help protect brain function in people with multiple sclerosis (MS). Researchers will use brain scans to measure changes in brain metabolism and inflammation in 55 MS patients who receive either …

This early-stage study is testing whether higher doses of radiation can be safely given to patients with aggressive or returning brain tumors called meningiomas. Researchers are using advanced PET and MRI scans to precisely target the radiation while carefully monitoring for side…

This early-stage study is testing the safety and best dose of a three-drug combination for patients with slow-growing non-Hodgkin's lymphoma that has returned or not responded to prior treatment. The drugs work together to help the immune system attack cancer cells and block a pr…

This early-stage trial is testing whether combining three different treatments is safe for men with aggressive prostate cancer. The approach uses a hormone-blocking drug (enzalutamide), radiation therapy, and standard hormone injections to attack the cancer from multiple angles. …

This study is testing whether a special type of ultrasound can accurately find prostate cancer. Men scheduled for prostate removal surgery receive a safe, short-lived contrast agent and then have an ultrasound scan. Researchers will compare the ultrasound images to the actual pro…

This study is testing a new wearable neck sensor designed to catch dangerous breathing slowdowns caused by opioid painkillers after surgery. Researchers will compare the sensor's readings to standard hospital monitors on 120 patients to see if it can accurately detect and even pr…

This study is testing whether taking ketone or hawthorn extract supplements for about 8 weeks can help people with congestive heart failure. Researchers want to see if these supplements can improve how well the heart works and increase a person's ability to exercise. About 45 par…

This study compares three different pain management approaches for adults aged 55+ with multiple broken ribs. Researchers want to see which method best reduces pain and opioid medication use while helping patients breathe better. The trial involves 24 hospitalized patients who wi…

This study is testing whether gentle electrical and magnetic stimulation applied to the skin over the spine can help improve movement and reduce muscle stiffness in people with long-term spinal cord injuries. Researchers will work with 10 participants to find the best stimulation…

This study is testing whether a special earbud device, which gently stimulates a nerve in the ear, can help reduce anxiety and emotional distress in healthcare workers. Researchers will enroll about 90 stressed healthcare professionals from Philadelphia to use the device for thre…

This study is testing a web-based virtual meeting tool designed to help healthcare providers discuss prostate cancer genetics cases. Doctors and other providers use the tool to talk about genetic testing, personalized treatment options, and screening recommendations. Researchers …

This study aims to understand how stress, depression, and social factors might affect liver disease progression in Korean Americans living with chronic hepatitis B. Researchers will follow 365 participants over time, collecting health information and hair samples to measure stres…

This study aimed to understand how head and neck cancer treatment affects patients' sleep quality over time. Researchers planned to survey patients at different stages of their treatment and recovery to identify factors that disrupt sleep. The goal was to gather information that …

This study aims to understand what helps or prevents people from getting screened for colorectal cancer, particularly in African American, Latinx, and Chinese communities. Researchers will conduct interviews and group discussions to learn about cultural beliefs and knowledge gaps…