Bubble contrast could reveal prostate cancer without a needle
NCT ID NCT05336786
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This phase III trial is testing whether a special ultrasound contrast agent, called Definity, can help doctors see prostate cancer on ultrasound images. The study involves 70 men scheduled for prostate removal surgery. Before surgery, they receive an IV of Definity, which contains tiny gas-filled bubbles that enhance ultrasound images. The goal is to see if this non-invasive method can accurately identify cancer sites in the prostate.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Perflutren lipid microspheres (Definity)
What this could lead to
If successful, this could provide a non-invasive way to identify prostate cancer, potentially reducing the need for biopsies.
What could go wrong
This is a small, early-phase study with only 70 participants, and the technique may not be accurate enough to replace standard methods. The contrast agent also carries a small risk of allergic reactions.
Disclaimer
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Amsterdam University Medical Centers
Amsterdam, Netherlands
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Sidney Kimmel Cancer Center at Thomas Jefferson University
Philadelphia, Pennsylvania, 19107, United States