Pee test could spot prostate cancer early

NCT ID NCT04788277

Ongoing Diagnosis Sponsor: Thomas Jefferson University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 01, 2026 · Updated 3 times

Summary

This study is testing a new way to detect prostate cancer by looking at cells in urine using a special imaging method. Researchers will collect urine samples from 675 men aged 50-75, including those with and without prostate cancer. The goal is to see if this simple test can accurately identify cancer and how aggressive it might be, potentially offering a non-invasive alternative to biopsies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Urine sample collection and optical imaging test
What this could lead to: If successful, this could lead to a simple, non-invasive urine test to detect prostate cancer, reducing the need for biopsies.
What could go wrong: This is an early-stage study focused on accuracy. The test may not be sensitive or specific enough to replace current methods, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

benign prostatic hyperplasia prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CARCINOMA

Contacts and locations

Locations

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, 19107, United States

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