Thomas Jefferson University

This study tested whether giving a standard multiple myeloma drug at home is a practical option for patients. Twenty adults already receiving the drug Darzalex Faspro received some of their injections at home instead of at the cancer center. The main goal was to see if home treat…

This study tested if providing special meals designed for diabetes and nutrition coaching via video calls could help people with poorly controlled type 2 diabetes. Researchers compared these supports to usual medical care to see if they improved blood sugar levels, weight, and qu…

This study tested whether using technology could help breast cancer patients stick to their long-term hormone therapy after surgery. Researchers compared standard doctor visits to two tech-based approaches: one using automated symptom surveys with follow-up video calls, and anoth…

This study tested whether using a special ultrasound technique could improve radiation treatment for liver cancer. Researchers gave patients an injection of tiny gas-filled bubbles and then used ultrasound to 'pop' them in the tumor area, hoping this would make the cancer cells m…

This study investigated whether nutritional supplements with antioxidant properties could help support brain function in people with Parkinson's disease. Researchers tested an oral and intravenous supplement called N-acetyl cysteine (NAC) in 51 patients with early-stage Parkinson…

This study tested a targeted radiation treatment for patients whose eye melanoma had spread to the liver. Doctors injected tiny radioactive beads directly into the liver's blood vessels to try to shrink the tumors. The goal was to see if this approach was safe and effective at co…

This study tested whether an intensive smoking cessation program could help head and neck or lung cancer patients quit smoking. The program included counseling, medications, and nicotine replacement therapy, and was compared to standard doctor advice. Researchers wanted to see if…

This study tested two different ultrasound methods for monitoring breast cancer in women who have had reconstruction surgery after mastectomy. Researchers compared automated breast ultrasound (which uses a machine) with handheld ultrasound (performed by a technician) to see which…

This study tested a new, noninvasive ultrasound technique to measure pressure inside the skull. Researchers compared the new scan, which uses a special contrast agent, to the standard method of a lumbar puncture (spinal tap) in 19 adults. The goal was to see if the painless scan …

This study tested a special ultrasound scan that uses tiny gas bubbles to see inside liver tumors. The goal was to see if this scan could predict how well a targeted radiation treatment would work for bile duct cancer. Researchers also tested if using the ultrasound to 'pop' thes…

This study aimed to find the best way to prevent women from having another preterm birth. It compared a vaginal progesterone treatment to a progesterone injection, both given during pregnancy. The trial involved 210 pregnant women who had delivered a baby early in a previous preg…

This study tested if a special vacuum-sealed bandage (called Prevena) could prevent wound problems after leg artery surgery. It focused on patients at high risk for complications like infections or wounds reopening. Researchers compared the vacuum dressing to standard bandages to…

This study tested whether a special vacuum-sealed dressing called PREVENA could prevent wound complications after leg amputation surgery. Researchers compared this dressing to standard wound care in 272 adults who had above- or below-knee amputations. They tracked whether the spe…

This study tested a personalized, home-based exercise program for women whose breast cancer has spread to other parts of the body. The 6-week virtual program, led by a cancer exercise specialist, aimed to help participants safely increase their physical activity. Researchers want…

This small pilot study explored whether an 8-week mindfulness meditation program could help prevent 'chemo brain'—the memory and concentration problems some people experience after chemotherapy. The study enrolled 15 women with breast cancer who were about to start chemotherapy. …

This study tested a new web-based education tool designed to help men with advanced or high-risk prostate cancer understand genetic testing. Researchers compared the online tool to traditional genetic counseling to see if it was just as good at helping patients make informed deci…

This study aimed to check the safety of a specific pain-blocking method used during chest surgery. Researchers measured the levels of the numbing drug ropivacaine in the blood of 20 patients to see if it reached potentially toxic amounts. They also tracked patients' pain, opioid …

This study compared two ways to help patients breathe while being moved from the operating room to the intensive care unit after major heart surgery. Researchers looked at whether using a portable breathing machine or a manual hand-pumped bag was better at keeping patients' oxyge…

This study tested whether a peer-led education program could help African American men better understand the risks and benefits of genetic screening for prostate cancer. Researchers worked with 149 men, with or without a family history of prostate cancer, to see if learning from …

This study collected leftover tumor tissue and blood samples from 141 patients during their cancer surgery. Researchers analyzed these samples in the lab to understand how many living cancer cells could be recovered and studied. The goal is to gather information that will help sc…

This study aimed to understand why aspirin helps some, but not all, high-risk pregnant people avoid preeclampsia, a serious blood pressure disorder. Researchers followed 130 pregnant people at high risk for preeclampsia who were taking aspirin. They checked blood markers, genetic…

This study followed 105 pregnant women with COVID-19 to understand how their immune response affects their babies. Researchers tracked antibody levels in mothers and newborns, and also studied how COVID-19 vaccines work during pregnancy and breastfeeding. The goal was to gather i…

This study aims to understand how Thyroid Eye Disease affects people's emotional well-being and daily life. Researchers interviewed 20 patients and caregivers about their experiences with mood, relationships, work, and leisure activities. The goal is to better document the psycho…

This study followed 150 pregnant and breastfeeding women who received a COVID-19 booster shot. Researchers collected blood, breast milk, and infant samples to measure how well protective antibodies passed from mother to baby. The goal was to understand how vaccination during preg…