The First Affiliated Hospital Of Guangzhou Medical University

This trial tests whether an intelligent breathing exercise device helps people recover lung function after surgery for non-small cell lung cancer. Participants use the device for breathing exercises twice daily for 30 days after surgery, while a comparison group receives standard…

This study tests a new targeted cancer pill called limertinib combined with brain radiation as a first treatment for people with a specific type of lung cancer (EGFR-mutant NSCLC) that has spread to the brain. The goal is to see if the combination can better control the brain tum…

This study tests whether a spontaneous-breathing anesthesia strategy (using a laryngeal mask instead of a breathing tube) can help adults recover faster after lung transplant. About 110 participants in China will receive this 'tubeless' approach during surgery. Researchers will m…

This study looks at whether keeping patients' natural breathing during lung transplant surgery helps them recover faster. It involves 60 adults aged 70 and older with end-stage lung disease. Instead of using a breathing tube and machine, doctors will use a mask and nerve blocks t…

This study looks at a new way to manage anesthesia during lung transplants for patients who are severely underweight (BMI under 16). Instead of using a breathing tube and machine, doctors will try to keep patients breathing on their own during surgery. The goal is to see if this …

This study tests a new anesthesia method that lets patients breathe on their own during lung transplant surgery, instead of using a breathing tube. Researchers want to see if this approach helps patients recover faster and need less breathing support after surgery. The study will…

This study tests a combination of two drugs, SHR-A1811 and pertuzumab, in people with advanced non-small cell lung cancer that has HER2 mutations or overexpression and has worsened after at least one prior treatment. The goal is to see if this combo can shrink tumors or slow dise…

This early-phase study tests a new treatment for people with early-stage lung cancer that can be removed by surgery. The treatment combines NK cells (a type of immune cell), an immunotherapy drug (PD-1 antibody), and standard chemotherapy given before surgery. The main goals are …

This phase 2 trial tests the drug golidocitinib in 16 people with advanced lung cancer who have severe blood problems caused by immunotherapy. The goal is to see if the drug can safely improve blood counts and reduce symptoms. Participants take the drug until their blood levels r…

This study tests a gene therapy called Gendicine, given as a mist to breathe in, for people with multiple ground-glass lung nodules — spots that may turn into cancer. About 38 adults will receive the treatment and be monitored with CT scans to see if the nodules shrink or disappe…

This study evaluates a portable device that measures lung function using oscillometry—a technique that sends gentle sound waves into the lungs—to diagnose chronic respiratory diseases like COPD, asthma, and bronchiectasis. Researchers will enroll about 4,000 adults across 50 cent…

This study looks at whether the shingles vaccine can prevent shingles and improve survival in 500 lung cancer patients. Participants will either receive the vaccine or not, and researchers will track shingles cases and survival rates over time. The goal is to see if the vaccine o…

This study tests whether a herbal medicine called Lifei Qingchang Granules can improve breathing and quality of life in people with stable bronchiectasis, a chronic lung condition. About 150 adults aged 18-75 who have had at least one flare-up in the past year will take either th…

This study compares a 'tubeless' approach to standard care for people having minimally invasive surgery to remove small lung nodules. The tubeless group gets a laryngeal mask instead of a breathing tube and no chest drain after surgery. The goal is to see if they recover better w…

This study looks at whether removing the chest tube right after lung surgery (called a tubeless strategy) helps patients recover faster with less pain. About 300 adults having a specific type of lung surgery will be randomly assigned to one of three groups: standard chest tube, o…

This study compares a newer anesthesia method where patients breathe on their own during lung surgery to the standard method using a breathing tube and machine. About 1,600 people having minimally invasive lung nodule removal will be randomly assigned to one of the two methods. T…

This study tests a new approach for people with multiple lung nodules who need surgery for at least one nodule. The method combines robot-assisted CT-guided ablation or localization with a less invasive surgery that avoids a breathing tube. The goal is to see if this combined tre…

This study tests whether using a laryngeal mask instead of a breathing tube during esophageal cancer surgery can reduce complications and speed up recovery. About 500 adults with resectable esophageal cancer will be randomly assigned to one of two anesthesia methods. The goal is …

This study will follow 200 adults who have had one lung nodule removed but still have other nodules in their lungs. Researchers will collect small blood samples during routine check-ups to study immune cells and virus-related markers. The goal is to see if certain immune patterns…

This study looks at immune cells in the blood of adults who have had one lung nodule removed but still have other nodules that need monitoring. Researchers will collect small blood samples during routine follow-up visits to analyze immune cell types and markers of past viral infe…