The First Affiliated Hospital Of Guangzhou Medical University

This study tests a drug called golidocitinib in 16 people with advanced lung cancer who have severe, hard-to-treat blood problems caused by immunotherapy. The goal is to see if the drug can safely reverse these blood side effects. Participants must not have had cancer growth in t…

This study looks at whether letting patients breathe on their own during lung transplant surgery helps them recover faster. It involves 60 adults aged 70 and older with end-stage lung disease. The goal is to see if this approach reduces the need for a breathing machine after surg…

This study looks at whether keeping patients breathing on their own during and after lung transplant surgery can help very underweight people recover faster. It will include 56 adults with end-stage lung disease and a very low body mass index. The main goals are to see if fewer p…

This study looks at whether a special anesthesia and surgery method that helps patients breathe on their own during a lung transplant can speed up recovery and improve survival. About 40 adults with end-stage lung disease who need a rescue transplant will take part. The main goal…

This study tests a new targeted drug (limertinib) combined with radiation therapy as a first treatment for people with a specific type of lung cancer (EGFR-mutant non-small cell lung cancer) that has spread to the brain. The goal is to see if the combination can better control br…

This study tests if inhaling a gene therapy called Gendicine can shrink or eliminate multiple ground-glass lung nodules, which are often precancerous. About 38 adults with these nodules will receive the treatment through a nebulizer. Doctors will monitor nodule changes with CT sc…

This study tests a new anesthesia and surgery method that lets lung transplant patients breathe on their own during and after the operation, avoiding a breathing tube. Researchers want to see if this 'tubeless' approach helps patients leave the hospital sooner and stay safe. Abou…

This early-phase study tests a new treatment for people with operable non-small cell lung cancer. It combines NK010 immune cells, an immunotherapy drug (PD-1 antibody), and standard chemotherapy given before surgery to shrink tumors. The main goals are to check safety and see how…

This study tests a combination of two drugs (SHR-A1811 and pertuzumab) in 60 adults with advanced non-small cell lung cancer that has a specific change called HER2 alteration and has worsened after at least one prior treatment. The goal is to see if the combo can shrink tumors or…

This study looks at whether the shingles vaccine can prevent shingles and improve survival in 500 adults with lung cancer. Participants will be observed for 12 months to see who gets shingles and how long they live. The goal is to find out if this vaccine is safe and effective fo…

This study looks at whether leaving out the chest tube after keyhole lung surgery helps patients recover faster and feel less pain. About 300 adults having surgery for lung nodules will be randomly assigned to one of three groups: standard chest tube, one suction, or two suctions…

This study tests whether avoiding breathing tubes and chest drains during minimally invasive lung surgery helps people recover faster. 138 adults with small lung nodules will be randomly assigned to either the tubeless approach or standard care. The main goal is to see if more pe…

This study tests whether using a laryngeal mask instead of a breathing tube during minimally invasive esophageal cancer surgery can reduce complications and speed up recovery. About 500 adults with resectable esophageal cancer will be randomly assigned to one of two anesthesia me…

This study tests whether a Chinese herbal medicine called Lifei Qingchang Granules can help people with stable bronchiectasis breathe easier and feel better. About 150 adults aged 18-75 who have had at least one flare-up in the past year will take either the granules or a placebo…

This study compares a newer anesthesia method where patients breathe on their own during lung surgery to the traditional method using a breathing tube and machine. About 1,600 adults with small lung nodules will be randomly assigned to one of the two methods. The goal is to see i…

This study tests a new way to treat people who have several lung nodules. It combines robot-assisted CT-guided ablation (using heat to destroy some nodules) with a less invasive keyhole surgery (NiVATS) to remove the main nodule, all during one hospital stay. The goal is to see i…