Could skipping the breathing tube make lung surgery recovery easier?

NCT ID NCT07395375

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study compares a newer anesthesia method where patients breathe on their own during lung surgery to the standard method using a breathing tube and machine. About 1,600 people having minimally invasive lung nodule removal will be randomly assigned to one of the two methods. The goal is to see if the newer method is just as safe and leads to a better recovery experience, with less pain and fewer side effects.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
non-intubated anesthesia (spontaneous breathing with laryngeal mask and nerve blocks)
What this could lead to
If successful, this could show that avoiding a breathing tube during lung surgery is safe and leads to a faster, more comfortable recovery.
What could go wrong
This is an early-stage comparison study, not a treatment trial. The non-intubated method may not prove safer or better, and results may not apply to all patients or surgeries.

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Conditions

The condition(s) this trial relates to.

lung neoplasm Multiple Pulmonary Nodules

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The First Affiliated Hospital of GZMU

    Guangzhou, China

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