Robot-Assisted combo treatment aims to ease lung nodule recovery
NCT ID NCT07395362
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new approach for people with multiple lung nodules who need surgery for at least one nodule. The method combines robot-assisted CT-guided ablation or localization with a less invasive surgery that avoids a breathing tube. The goal is to see if this combined treatment is safe and can be done successfully, with a focus on reducing complications and speeding up recovery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Feb 2026
An estimate. Start dates often move.
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age 18 to 85 years at the time of enrollment. 2. Presence of multiple pulmonary nodules identified on chest computed tomography (CT). 3. At least one dominant pulmonary lesion meeting standard indications for thoracoscopic surgical resection based on radiologic assessment. 4. At least one additional pulmonary nodule for which complete surgical resection is considered undesirable due to lung parenchyma preservation concerns or procedural risk, and deemed suitable for robot-assisted CT-guided percutaneous intervention. 5. Determined by a multidisciplinary team (MDT) to be an appropriate candidate for the predefined hybrid treatment strategy. 6. Eligible for non-intubated video-assisted thoracoscopic surgery based on preoperative anesthetic evaluation (ASA physical status I-III). 7. Ability to understand the study procedures and provide written informed consent. Exclusion Criteria: 1. Pulmonary nodules located centrally or adjacent to major airways, major vessels, or the heart, where safe percutaneous intervention is not feasible. 2. Pure ground-glass nodules with a maximum diameter \< 6 mm, for which active surveillance is recommended. 3. Clinical evidence of N1/N2 lymph node involvement or distant metastasis. 4. Severe cardiopulmonary disease, interstitial lung disease, or other conditions that preclude thoracoscopic surgery or anesthesia. 5. Coagulation disorders or ongoing anticoagulation therapy that cannot be safely discontinued. 6. Pregnancy or breastfeeding. 7. Any condition that, in the opinion of the investigator, would make participation unsafe or interfere with study assessments.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The First Affiliated Hospital of GZMU
Guangzhou, China
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Other studies related to the condition(s) this trial covers.
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